NOPE! That show is just the same old BS dressed up slightly differently. Micro-expressions have been debunked pretty soundly as nothing but junk science. Just because the FBI happens to consider this useful doesn't mean much, they still use the polygraph! These are just tools of intimidation which are effectively used against ignorant people who have no science background. The way the ploy works is that a supposed expert claims that he knows that the suspect is lying (either based on polygraph results or by studying micro-expressions caught on video tape) and the suspect "realizes" that he/she won't succeed in deceiving these "savvy" detectives and so the suspect confesses. There's a reason that micro-expressions and polygraphs can't be used in a court of law. They have been shown (rather mercilessly) to be complete and utter BS. Shows like the one you're talking about are just propaganda encouraged (funded) by companies that profit from this sort of thing. The fact that Popular Mechanics actually ran an editorial professing that micro-expressions were of value speaks rather poorly of the author of the editorial and of the magazine.
At the show's center is Cal Lightman (Tim Roth), a scientist whose expertise is detecting and interpreting "micro" expressions—involuntary facial expressions that last just a moment—a useful skill if you want to want to figure out whether someone's lying, and why. Lightman runs a consulting firm from which he and three supporting characters traverse the Washington, D.C., area solving mysteries for the police, FBI and pretty much any other client who needs a lie detector.
It is completely inaccurate to refer to Cal Lightman (Tim Roth) as a scientist since real scientists would never waste time on something as poorly defined and subjective as micro-expressions. While this Cal Lightman (Tim Roth) might pretend to be a scientist and gullible members of the general public might buy into the show, anyone capable of generating alternate hypotheses sees through the BS pretty quickly! This Cal Lightman (Tim Roth) is either a moron who really believes the BS he's pedaling or he's a liar (as pointed out earlier by another poster in regards to the polygraph).